Tonic release of glutamate by a DIDS-sensitive mechanism in rat hippocampal slices
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چکیده
منابع مشابه
Oxiracetam increases the release of endogenous glutamate from depolarized rat hippocampal slices.
Nootropics are drugs employed to improve cognitive functions, particularly learning and memory ability, and to prevent their impairment following cerebral damage (Moos et al., 1988). Oxiracetam (4-hydroxy-2-oxopyrrolidinoacetamide) has been reported to enhance learning and memory in normal animals as well as in animals bearing different types of cerebral impairment. Clinical effects of oxiracet...
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متن کاملCryopreservation of rat hippocampal slices by vitrification.
Although much interest has attended the cryopreservation of immature neurons for subsequent therapeutic intracerebral transplantation, there are no reports on the cryopreservation of organized adult cerebral tissue slices of potential interest for pharmaceutical drug development. We report here the first experiments on cryopreservation of mature rat transverse hippocampal slices. Freezing at 1....
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 2005
ISSN: 0022-3751
DOI: 10.1113/jphysiol.2004.082131